Nexturastat A

CAS No. 1403783-31-2

Nexturastat A ( Nexturastat A )

Catalog No. M11689 CAS No. 1403783-31-2

A potent and selective HDAC6 inhibitor with IC50 of 5 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 81 In Stock
10MG 105 In Stock
25MG 177 In Stock
50MG 286 In Stock
100MG 426 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Nexturastat A
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and selective HDAC6 inhibitor with IC50 of 5 nM.
  • Description
    A potent and selective HDAC6 inhibitor with IC50 of 5 nM; displays >100-fold selectivity over other HDAC isozymes (600-fold relative to the inhibition of HDAC1).
  • Synonyms
    Nexturastat A
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC6
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1403783-31-2
  • Formula Weight
    341.40
  • Molecular Formula
    C19H23N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 56 mg/mL
  • SMILES
    O=C(NO)C1=CC=C(CN(CCCC)C(NC2=CC=CC=C2)=O)C=C1
  • Chemical Name
    Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bergman JA, et al. J Med Chem. 2012 Nov 26;55(22):9891-9.
2. Miyake Y, et al. Nat Chem Biol. 2016 Sep;12(9):748-54.
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